Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens.

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Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens.

Mucosal biopsy specimens from the ileal reservoirs of 92 patients who had undergone restorative proctocolectomy (12 with familial adenomatous polyposis, 78 with ulcerative colitis, and two with functional bowel disease) were studied. Chronic inflammation was found in almost all, as was villous atrophy of varying severity. Other changes included pyloric metaplasia and mucosal prolapse. Acute inf...

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Restorative Proctocolectomy with Ileal Reservoir: Pouch Configuration and Volume

Restorative proctocolectomy with ileal reservoir has become an accepted form of treatment for ulcerative colitis and familial adenomatous polyposis. Five types of reservoirs have been developed: the S pouch, J pouch, H pouch, W pouch and K pouch. This paper reviews the differences in the clinical and functional outcomes among the various reservoir designs and their sizes. From the results of th...

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Restorative proctocolectomy with ileal reservoir: a pathophysiological assessment.

A metabolic and physiological assessment was carried out in 14 patients who had undergone restorative proctocolectomy with ileal reservoir more than six months previously. The haemoglobin was normal in all but one and plasma electrolytes and serum albumin, calcium, phosphorus, and red cell folate estimations were normal in all. Five patients had low serum iron levels of whom one had an iron def...

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Adverse metabolic sequelae following restorative proctocolectomy with an ileal pouch.

Ileal pouch-anal anastomosis (IPAA) following total proctocolectomy has become the surgical treatment of choice for ulcerative colitis patients who have medically refractory disease or neoplasia. Unfortunately, various metabolic complications have been reported with this surgical procedure, including anemia, vitamin B(12) deficiency, bile salt and fat malabsorption, vitamin D deficiency, bone l...

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Confocal laser endomicroscopy for the detection of mucosal changes in ileal pouch after restorative proctocolectomy.

BACKGROUND Pouchitis and dysplasia may affect the reservoir after restorative proctocolectomy. AIMS To assess the suitability of confocal laser endomicroscopy for the in vivo diagnosis of mucosal changes in ileal pouch for ulcerative colitis and familial adenomatous polyposis. METHODS Standard endoscopy and endomicroscopy were performed in 18 pouches. Confocal images were scored for the pre...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1987

ISSN: 0021-9746

DOI: 10.1136/jcp.40.6.601